Cyclophosphamide pneumonitis.

Effects of corticosteroids and cyclophosphamide on a mouse model of Chlamydia trachomatis pneumonitis.

Suppression of the inflammatory reaction with daily doses of cortisone acetate or cyclophosphamide substantially prolonged the pulmonary infection in mice which had been intranasally inoculated with a trachoma biotype of Chlamydia trachomatis. Titration of organisms recovered from the lungs of treated mice revealed a drop in titer after day 2 (postinfection), followed by a prominent increase on...

Pneumonitis

Desquamative interstitial pneumonitis vs usual interstitial pneumonitis.

My colleague and collaborator, the late Edgar G. Harrison, Jr., M.D., was of the opinion that “desquamation” was a fundamental phenomenon in the spectrum of usual interstitial pneumonitis. In our report’ on classic interstitial pneumonitis-flbrosis, we found that almost two-thirds of our biopsies revealed this finding. Harrison believed that the designation, “desquamative interstitial pneurnoni...

Desquamative Interstitial Pneumonitis vs Usual Interstitial Pneumonitis

My colleague and collaborator, the late Edgar G. Harrison, Jr., M.D., was of the opinion that “desquamation” was a fundamental phenomenon in the spectrum of usual interstitial pneumonitis. In our report’ on classic interstitial pneumonitis-flbrosis, we found that almost two-thirds of our biopsies revealed this finding. Harrison believed that the designation, “desquamative interstitial pneurnoni...

Acute Pneumonitis

During the past seven years several reports of an acute type of pulmonary infection, characterized by an onset with headache, malaise, and mild cough and by a febrile course of about a week's duration, with a minimum of adventitious signs on examination of the chest, little or no leukocytosis or sputum, and x-ray signs of evidence of pulmonary infection far out of proportion to the patient's cl...